Abstract
A Meta-Analysis on the Effectiveness of Endoscopic Gastric Balloon Placement versus Endoscopic Sleeve Gastroplasty for the Management of Obesity
Natasha Bernadine Abela-Mapa, MD; Marc Julius Navarro, MD
Makati Medical Center
Significance: Managing obesity that does not respond to lifestyle change or pharmacotherapy poses significant challenges, especially in determining the best intervention. The situation emphasizes the challenge of maintaining weight loss over time and the importance of using comprehensive strategies to effectively address obesity. In the recent years, bariatric surgery, such as gastric bypass and sleeve gastroplasty, offers significant weight loss and metabolic advantages, especially for those with severe obesity or obesity-related health conditions.
Methodology: A meta-analysis was performed using 4 studies which directly compared the effectiveness of endoscopic gastric balloon (EGB) placement versus endoscopic sleeve Gastroplasty (ESG) for management of obesity. Electronic databases such as The Cochrane Library, Pubmed, Google Scholar, and Science Direct were searched for relevant studies on May 01 2024 using the search strategy: (gastric balloon placement) AND (sleeve Gastroplasty) AND (obesity). Random effects meta-analysis was performed to compute for mean difference and risk ratio to pool individual study data.
Results: The pooled mean difference showed that ESG is associated with higher %TBWL than EGB at 1 month (MD=-2.3, 95%CI=-4.1 to -0.6, p=0.009) and at 12 months (MD=-7.6, 95%CI=-10.8 to -4.5, p<0.00001). No significant difference was observed in the 6 months period (MD=-2.3, 95%CI=-5.3 to 0.7) and in terms of adverse events (RR=1.6, 95%CI= 0.2 to 12.8).
Conclusion: We observed a higher benefit of ESG for weight loss compared to EGB among obese individuals. Both interventions are equally safe and not associated with serious adverse events.
Important Dates to Remember
| JRRE Activities 2023-2024 |
Proposed Dates |
|---|---|
| Resumption of face-to-face Evidence-Based Medicine Workshop Venue to be announced once finalized. |
July 21, 2023 (Friday), 1-5pm |
| Monthly Critical Appraisal of Topics Conferences to be gaciliated by Research Coordinators per Institution | Monthly Critical Appraisal of Topics Conferences per Institution |
| CAT Plenary/Liver Con Dates: September 23, 2023 December 16, 2023 March 2024 (During the JAC) Resumption of face-to-face Quarterly Critical Appraisal of Topics facilitated by the JRRE |
2 Clinical scenarios and articles are to be sent to institutions each on August 2023, November 2023, and February 2024; |
| Hybrid Research Workshop 4 week asynchronous via Moodle, followed by a 1 day on-site Onsite Workshop Research Protocol Presentation for Level I GI Fellows-In-Training - Research Protocol Presentation: August 12, 2023 - Research Forums of the Tripartite Societies |
Week 1: July 15-21, 2023 Week 2: July 22-28, 2023 Week 3: July 29-August 4, 2023 Week 4: August 5-11, 2023 |
| Research Manuscript Workshop for level II GI Fellows-In-Training | January 6, 2024 |