Abstract
Incidence and Risk Prediction Score of Refeeding Syndrome in Hospitalized Patients Admitted in a Public Tertiary Hospital: A Prospective, Analytical Single Center Study
Jane Loue E. Gargaritano, MD; Maricel Malazarte, MD
Vicente Sotto Memorial Medical Center
Significance: Refeeding syndrome (RFS) is a potentially life-threatening metabolic complication that can occur in malnourished individuals who are rapidly reintroduced to nutritional support. Unfortunately, there is scarce data on the incidence of RFS among them. We aim to determine the incidence of RFS and aid clinicians in identifying its possibility using practical clinical parameters.
Methodology: In this prospective, analytical study conducted between October 2022 to December 2023, 217 patients were evaluated for risk of developing RFS. Patients were grouped into RFS and non-RFS groups based on the occurrence of hypophosphatemia. All significant factors for the development of RFS were subjected to binary logistic regression and were aggregated to develop a new risk scoring model. The Cox and Snell R Square was used to determine the goodness of fit of the model and the receiver operator characteristic curve (AUROCC) was used to determine its overall accuracy.
Results: Among 217 patients, 32% were at risk for malnutrition. RFS occurred in 20%. Binary logistic regression analyses showed that predictors of RFS include lower magnesium, potassium and albumin levels and lower total protein delivered (p<0.05). Using the predictive model, the AUROCC recorded an overall accuracy rate of 77.6% which is considered an acceptable discriminating power to determine the likelihood to develop RFS.
Conclusion: The incidence of RFS among malnourished patients in this institution is high. The risk prediction model has acceptable predictive effects and clinical utility which may be used as a reference for screening for RFS risk in malnourished patients.
Important Dates to Remember
| JRRE Activities 2023-2024 |
Proposed Dates |
|---|---|
| Resumption of face-to-face Evidence-Based Medicine Workshop Venue to be announced once finalized. |
July 21, 2023 (Friday), 1-5pm |
| Monthly Critical Appraisal of Topics Conferences to be gaciliated by Research Coordinators per Institution | Monthly Critical Appraisal of Topics Conferences per Institution |
| CAT Plenary/Liver Con Dates: September 23, 2023 December 16, 2023 March 2024 (During the JAC) Resumption of face-to-face Quarterly Critical Appraisal of Topics facilitated by the JRRE |
2 Clinical scenarios and articles are to be sent to institutions each on August 2023, November 2023, and February 2024; |
| Hybrid Research Workshop 4 week asynchronous via Moodle, followed by a 1 day on-site Onsite Workshop Research Protocol Presentation for Level I GI Fellows-In-Training - Research Protocol Presentation: August 12, 2023 - Research Forums of the Tripartite Societies |
Week 1: July 15-21, 2023 Week 2: July 22-28, 2023 Week 3: July 29-August 4, 2023 Week 4: August 5-11, 2023 |
| Research Manuscript Workshop for level II GI Fellows-In-Training | January 6, 2024 |