Abstract
A Case Series of Duodenal and Pancreatic Metastasis from Renal Cell Carcinoma: Unusual locations of gastrointestinal metastasis
Aaron Y. Ong, M.D. 1, Janus P. Ong, M.D. 1, Ruter M. Maralit M.D. 1
Division of Gastroenterology, Department of Medicine, University of the Philippines-Philippine General Hospital
Background: Renal cell carcinoma (RCC) metastasizing to the duodenum and pancreas are rare and unusual sites of metastasis with literature listing only a handful of case reports.
Clinical Presentation: We report two cases of duodenal and pancreatic metastasis of renal cell carcinoma, respectively. The first case is a known case of stage II RCC presenting with melena and weight loss 13 years after radical nephrectomy. Computed tomography revealed hepatic and pancreatic masses. On upper endoscopy noted a friable mass at the first segment of the duodenum where a biopsy taken was consistent with metastatic RCC. The second case is a known RCC case who presented with vague abdominal discomfort ten years after radical nephrectomy. Positron emission tomography revealed a pancreatic head mass. Biopsy taken of the said mass via endoscopic ultrasound revealed metastatic RCC. Both patients underwent palliative radiotherapy.
Conclusion: In patients who have underwent nephrectomy for RCC, metastasis to gastrointestinal sites must be kept in mind especially in those with gastrointestinal symptoms so that a thorough workup is not missed and endoscopic investigation can be carried out.
Keywords: Duodenum, renal cell carcinoma, metastasis, melena
Important Dates to Remember
| JRRE Activities 2023-2024 |
Proposed Dates |
|---|---|
| Resumption of face-to-face Evidence-Based Medicine Workshop Venue to be announced once finalized. |
July 21, 2023 (Friday), 1-5pm |
| Monthly Critical Appraisal of Topics Conferences to be gaciliated by Research Coordinators per Institution | Monthly Critical Appraisal of Topics Conferences per Institution |
| CAT Plenary/Liver Con Dates: September 23, 2023 December 16, 2023 March 2024 (During the JAC) Resumption of face-to-face Quarterly Critical Appraisal of Topics facilitated by the JRRE |
2 Clinical scenarios and articles are to be sent to institutions each on August 2023, November 2023, and February 2024; |
| Hybrid Research Workshop 4 week asynchronous via Moodle, followed by a 1 day on-site Onsite Workshop Research Protocol Presentation for Level I GI Fellows-In-Training - Research Protocol Presentation: August 12, 2023 - Research Forums of the Tripartite Societies |
Week 1: July 15-21, 2023 Week 2: July 22-28, 2023 Week 3: July 29-August 4, 2023 Week 4: August 5-11, 2023 |
| Research Manuscript Workshop for level II GI Fellows-In-Training | January 6, 2024 |