Abstract
ULCERATIVE COLITIS WITH IMMUNE THROMBOCYTOPENIC PURPURA: CASE REPORT
Escabarte, L. MD; Lim, E. MD
Department of Internal Medicine Section of Gastroenterology, Chinese General Hospital and Medical Center
Significance: Ulcerative colitis (UC) is characterized by inflammation limited to the colonic mucosa. UC is rarely described in association with hematologic abnormalities, such as immune mediated thrombocytopenia. Platelet count, which is also considered an inflammation marker, was usually higher among active UC. Ulcerative colitis (UC) is characterized by inflammation limited to the colonic mucosa. UC is rarely described in association with hematologic abnormalities, such as immune mediated thrombocytopenia. Platelet count, which is also considered an inflammation marker, was usually higher among active UC.
Clinical Presentation: Case of 19 year old male presenting with one month history of bloody diarrhea, with colicky abdominal pain and tenesmus. Physical examination revealed fresh blood on rectal examination; no palpable liver and spleen. Laboratory results showed low platelets at 29,000 per microliter. He was given 6 units of platelets, with platelet improvement to 46,000 per microliter. Peripheral blood smear showed quantitatively decreased platelet. Colonoscopy revealed diffuse erythematous colonic mucosa topped with exudates and pinpoint hemorrhages without active bleeding. Histopathology of colonic mucosa revealed colonic epithelium with areas of atypia and presence of crypt abscesses, cryptitis and rupture, compatible with diagnosis of UC. Patient was given Mesalazine 3000 mg and oral Prednisone 30 mg daily as treatment.
Keywords: Case report, ulcerative colitis, immune thrombocytopenic purpura
Important Dates to Remember
| JRRE Activities 2023-2024 |
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|---|---|
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