Abstract

NECROTIZING FASCIITIS IN A PATIENT WITH SIGNET RING GASTRIC ADENOCARCINOMA

Lorenz Kristoffer D. Daga MD
East Avenue, Diliman, Quezon City, Philippines

Significance: Necrotizing fasciitis is an aggressive infection of the skin and soft tissues that requires prompt recognition and management. Immediate source control and adjunctive antibiotic therapy are the cornerstone of management. There are limited reported cases of necrotizing fasciitis related to gastrointestinal malignancy, let alone related to gastric cancer. In this paper, a case of a 36-year old man who developed necrotizing fasciitis related to perforated gastric adenocarcinoma with signet-ring features was described. Signet-ring adenocarcinoma is associated with a more aggressive malignancy. The rapid progression of the infection leading to refractory shock and acute respiratory distress rendered the patient poor candidate for surgical source control because of high surgical risk. Immediate recognition of necrotizing fasciitis and perforated gastric cancer can prompt early surgical referral for definitive source control and gastric resection or repair.

Keywords: signet ring cell gastric adenocarcinoma; perforated gastric cancer; necrotizing fasciitis

Important Dates to Remember

JRRE Activities
2023-2024
Proposed Dates
Resumption of face-to-face Evidence-Based Medicine Workshop
Venue to be announced once finalized.
July 21, 2023 (Friday), 1-5pm
Monthly Critical Appraisal of Topics Conferences to be gaciliated by Research Coordinators per Institution Monthly Critical Appraisal of Topics Conferences per Institution
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September 23, 2023
December 16, 2023
March 2024 (During the JAC)
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