Abstract
Efficacy and Safety of Cholangiopancreatoscopy Using a Digital Cholangioscope: The Initial Experience from a Tertiary Hospital in Metro Manila
Ben Joseph P. Rodriguez, MD; Evan G. Ong, MD
Significance: Direct endoscopic visualization of biliary and pancreatic pathology is one of the most significant advances in diagnostic and therapeutic pancreaticobiliary endoscopy. Digital cholangioscopy using the SpyGlass DS system (Boston Scientific Corp., Natick, MA, USA) allows evaluation and treatment of intraductal lesions not possible by conventional means. This modality is relatively new in the local setting, and we aim to assess its usefulness, effectiveness and safety based on our initial experience.
Methodology: This is a single-center, retrospective, descriptive, cross-sectional study involving 40 patients who underwent ERCP with SpyGlass cholangiopancreatoscopy from June 2022 to December 2022. Outcomes measured were technical success, or the ability to get a visual evaluation of the pathology and complete the procedure as planned, as well as clinical success, described as either collection of specimens adequate for histologic evaluation using SpyBite forceps or initiation of stone fragmentation and removal. Rates of adverse events were also documented. Data were analyzed using Stata 13 (Stata Corp., College Park, Texas, USA).
Results: Technical success was achieved in 87.5% of cases, while clinical success was attained in 81.3%. Using the SpyBite forceps, 76.9% (10/13) of specimen acquired were adequate for histopathologic evaluation. Adverse events occurred in 15% (6/40); the most frequent was post-procedure pancreatitis (4; 10%). There was 1 case with cholangitis (2.5%), while another had bleeding (2.5%).
Keywords: ERCP, cholangioscopy, SpyGlass DS, adverse events, digital single-operator cholangioscopy, indeterminate biliary strictures, complex biliary stone disease
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